Bioanalytical Services

Protein Biomarker Discovery

High-Throughput Laboratory Services for Protein Profiling

BioXpedia offers high-throughput protein analyses, which support projects from large-scale biomarker discovery with relative quantification to low-plex absolute protein quantification or biomarker validation.

Our technologies for protein biomarker screening and protein quantification:

The Proximity Extension Assay allow you to measure 92 disease relevant proteins in one sample in predefined panels. Currently, 15 panels exist covering e.g. oncology, inflammation, cardiovascular disease and neurology. View all panels here.

Using Meso Scale Discovery immunoassays we can perform absolute protein quantification either as single analyte assays or multiplex assays with up to 10 analytes in each well.

Sample Types for Protein Biomarker Screening

The protein analyses we offer are primarily validated for human and murine samples, although immunoassays for other species are also available. The sample amount input is very low, down to 1 µl plasma, allowing you to get the most out of your precious samples. Types of samples are:

  • Plasma
  • Serum
  • Tissue lysate
  • Cell lysate or supernatant
  • CNF
  • .. and many more. Contact us for more information.

Applications

Protein screening or quantification has applications in many research areas, such as

  • Patient stratification
  • Development of personalized medicine
  • Drug target screening and discovery
  • Biomarker discovery for diagnosis and prognosis

 

For examples of publications presenting protein biomarker research, click here.